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A sodium channel knockin mutant (Na(V)1.4-R669H) mouse model of hypokalemic periodic paralysis

Hypokalemic periodic paralysis (HypoPP) is an ion channelopathy of skeletal muscle characterized by attacks of muscle weakness associated with low serum K(+). HypoPP results from a transient failure of muscle fiber excitability. Mutations in the genes encoding a calcium channel (Ca(V)1.1) and a sodi...

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Detalhes bibliográficos
Main Authors: Wu, Fenfen, Mi, Wentao, Burns, Dennis K., Fu, Yu, Gray, Hillery F., Struyk, Arie F., Cannon, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3195470/
https://ncbi.nlm.nih.gov/pubmed/21881211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI57398
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