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Bumetanide prevents transient decreases in muscle force in murine hypokalemic periodic paralysis

OBJECTIVE: To test the hypothesis that inhibition of the Na-K-2Cl transporter with bumetanide will reduce the susceptibility to decreases in muscle force in a mouse model of hypokalemic periodic paralysis (HypoPP). METHODS: In vitro contraction tests were performed on soleus muscle isolated from mic...

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Detalhes bibliográficos
Main Authors: Wu, Fenfen, Mi, Wentao, Cannon, Stephen C.
Formato: Artigo
Idioma:Inglês
Publicado em: Lippincott Williams & Wilkins 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3662304/
https://ncbi.nlm.nih.gov/pubmed/23427324
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e3182886a0e
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