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Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia
BACKGROUND: Hypokalemic periodic paralysis (HypoPP) is associated with mutations in either the Ca(V)1.1 calcium channel or the Na(V)1.4 sodium channel. Some Na(V)1.4 HypoPP mutations have been shown to cause an anomalous inward current that may contribute to the attacks of paralysis. Herein, we test...
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| 主要な著者: | , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Lippincott Williams & Wilkins
2011
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100087/ https://ncbi.nlm.nih.gov/pubmed/21490317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318219fb57 |
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