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Leaky sodium channels from voltage sensor mutations in periodic paralysis, but not paramyotonia
BACKGROUND: Hypokalemic periodic paralysis (HypoPP) is associated with mutations in either the Ca(V)1.1 calcium channel or the Na(V)1.4 sodium channel. Some Na(V)1.4 HypoPP mutations have been shown to cause an anomalous inward current that may contribute to the attacks of paralysis. Herein, we test...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Lippincott Williams & Wilkins
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3100087/ https://ncbi.nlm.nih.gov/pubmed/21490317 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1212/WNL.0b013e318219fb57 |
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