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Notch Signaling Pathway Enhances Bone Morphogenetic Protein 2 (BMP2) Responsiveness of Msx2 Gene to Induce Osteogenic Differentiation and Mineralization of Vascular Smooth Muscle Cells

Vascular calcification is regulated in a process similar to bone formation. BMP2 (bone morphogenetic protein 2) is essential for osteoblastic differentiation of mesenchymal progenitor cells and thus has been implicated in the development of vascular calcification. Here we examined whether Notch sign...

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Bibliografiset tiedot
Päätekijät: Shimizu, Takehisa, Tanaka, Toru, Iso, Tatsuya, Matsui, Hiroki, Ooyama, Yoshiaki, Kawai-Kowase, Keiko, Arai, Masashi, Kurabayashi, Masahiko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099727/
https://ncbi.nlm.nih.gov/pubmed/21471203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.175786
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