PIAS1 Mediates TGFβ-Induced SM α-Actin Gene Expression Through Inhibition of KLF4 Function-Expression by Protein Sumoylation

OBJECTIVE: TGFβ and proliferation/phenotypic switching of smooth muscle cells (SMCs) play a pivotal role in pathogenesis of atherosclerotic and restenotic lesions after angioplasty. We have previously shown that the protein inhibitor of activated STAT (PIAS)1 activates expression of SMC differentiat...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Kawai-Kowase, Keiko, Ohshima, Takayuki, Matsui, Hiroki, Tanaka, Toru, Shimizu, Takehisa, Iso, Tatsuya, Arai, Masashi, Owens, Gary K., Kurabayashi, Masahiko
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322553/
https://ncbi.nlm.nih.gov/pubmed/18927467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.172700
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker