PIAS1 Mediates TGFβ-Induced SM α-Actin Gene Expression Through Inhibition of KLF4 Function-Expression by Protein Sumoylation

OBJECTIVE: TGFβ and proliferation/phenotypic switching of smooth muscle cells (SMCs) play a pivotal role in pathogenesis of atherosclerotic and restenotic lesions after angioplasty. We have previously shown that the protein inhibitor of activated STAT (PIAS)1 activates expression of SMC differentiat...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kawai-Kowase, Keiko, Ohshima, Takayuki, Matsui, Hiroki, Tanaka, Toru, Shimizu, Takehisa, Iso, Tatsuya, Arai, Masashi, Owens, Gary K., Kurabayashi, Masahiko
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3322553/
https://ncbi.nlm.nih.gov/pubmed/18927467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.108.172700
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados