The homeobox transcription factor MSX2 partially mediates the effects of bone morphogenetic protein 4 (BMP4) on somatic cell reprogramming

Bone morphogenetic proteins (BMPs) induce mesenchymal–epithelial transition (MET) and enhance the generation of induced pluripotent stem cells (iPSCs). However, BMPs are also signaling molecules critical for arresting reprogramming in the pre-iPSC state. In this study, using mouse embryonic fibrobla...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Lin, Lilong, Liang, Lining, Yang, Xiao, Sun, Hao, Li, Yuan, Pei, Duanqing, Zheng, Hui
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2018
Subjects:
Cell Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153288/
https://ncbi.nlm.nih.gov/pubmed/30097516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.003913
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