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Human Cyclooxygenase-2 Is a Sequence Homodimer That Functions as a Conformational Heterodimer
Prostaglandin endoperoxide H synthases 1 and 2, also known as cyclooxygenases (COXs) 1 and 2, convert arachidonic acid (AA) to prostaglandin endoperoxide H(2). Prostaglandin endoperoxide H synthases are targets of nonspecific nonsteroidal anti-inflammatory drugs and COX-2-specific inhibitors called...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099718/ https://ncbi.nlm.nih.gov/pubmed/21467029 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.231969 |
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