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The Adaptor-associated Kinase 1, AAK1, Is a Positive Regulator of the Notch Pathway
The Notch pathway is involved in cell-cell signaling during development and adulthood from invertebrates to higher eukaryotes. Activation of the Notch receptor by its ligands relies upon a multi-step processing. The extracellular part of the receptor is removed by a metalloprotease of the ADAM famil...
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| Main Authors: | , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Biochemistry and Molecular Biology
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3099689/ https://ncbi.nlm.nih.gov/pubmed/21464124 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190769 |
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