The Adaptor-associated Kinase 1, AAK1, Is a Positive Regulator of the Notch Pathway

The Notch pathway is involved in cell-cell signaling during development and adulthood from invertebrates to higher eukaryotes. Activation of the Notch receptor by its ligands relies upon a multi-step processing. The extracellular part of the receptor is removed by a metalloprotease of the ADAM famil...

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Main Authors: Gupta-Rossi, Neetu, Ortica, Sara, Meas-Yedid, Vannary, Heuss, Sara, Moretti, Julien, Olivo-Marin, Jean-Christophe, Israël, Alain
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Cell Biology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099689/
https://ncbi.nlm.nih.gov/pubmed/21464124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.190769
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