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Protein Native State Stabilization by Placing Aromatic Side Chains in N-Glycosylated Reverse Turns

N-glycosylation of eukaryotic proteins helps them fold and traverse the cellular secretory pathway and can increase their stability, although the molecular basis for stabilization is poorly understood. Glycosylation of proteins at naïve sites (ones that normally are not glycosylated) could be useful...

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Detalles Bibliográficos
Main Authors: Culyba, Elizabeth K., Price, Joshua L., Hanson, Sarah R., Dhar, Apratim, Wong, Chi-Huey, Gruebele, Martin, Powers, Evan T., Kelly, Jeffery W.
Formato: Artigo
Idioma:Inglês
Publicado: 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099596/
https://ncbi.nlm.nih.gov/pubmed/21292975
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1198461
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