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Down-regulation of stathmin expression is required for megakaryocyte maturation and platelet production

The final stages of of megakaryocyte (MK) maturation involve a series of steps, including polyploidization and proplatelet formation. Although these processes are highly dependent on dynamic changes in the microtubule (MT) cytoskeleton, the mechanisms responsible for regulation of MTs in MKs remain...

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Detalhes bibliográficos
Main Authors: Iancu-Rubin, Camelia, Gajzer, David, Tripodi, Joseph, Najfeld, Vesna, Gordon, Ronald E., Hoffman, Ronald, Atweh, George F.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099574/
https://ncbi.nlm.nih.gov/pubmed/21364187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-305540
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