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Is normal hematopoiesis maintained solely by long-term multipotent stem cells?

The understanding of the hierarchical organization of the human hematopoietic system is of major biologic and clinical significance. The validity of the conventional model in which hematopoiesis is solely maintained by a pool of multipotent long-term hematopoietic stem cells (LT-HSCs) has been recen...

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Autors principals: Cavazzana-Calvo, Marina, Fischer, Alain, Bushman, Frederic D., Payen, Emmanuel, Hacein-Bey-Abina, Salima, Leboulch, Philippe
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099566/
https://ncbi.nlm.nih.gov/pubmed/21304104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-09-255679
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