Controlled Modulation of Folate Polyglutamyl Tail Length by Metabolic Engineering of Lactococcus lactis

The dairy starter bacterium Lactococcus lactis is able to synthesize folate and accumulates >90% of the produced folate intracellularly, predominantly in the polyglutamyl form. Approximately 10% of the produced folate is released into the environment. Overexpression of folC in L. lactis led to an in...

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Detalhes bibliográficos

Publicado no:	Appl Environ Microbiol
Principais autores:	Sybesma, Wilbert, van den Born, Erwin, Starrenburg, Marjo, Mierau, Igor, Kleerebezem, Michiel, de Vos, Willem M., Hugenholtz, Jeroen
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2003
Assuntos:	Food Microbiology
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC309937/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14660354/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/AEM.69.12.7101-7107.2003
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