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A Rapid, Extensive, and Transient Transcriptional Response to Estrogen Signaling in Breast Cancer Cells

We report the immediate effects of estrogen signaling on the transcriptome of breast cancer cells using Global Run-On and sequencing (GRO-seq). The data were analyzed using a new bioinformatic approach that allowed us to identify transcripts directly from the GRO-seq data. We found that estrogen sig...

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Detalhes bibliográficos
Main Authors: Hah, Nasun, Danko, Charles G., Core, Leighton, Waterfall, Joshua J., Siepel, Adam, Lis, John T., Kraus, W. Lee
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099127/
https://ncbi.nlm.nih.gov/pubmed/21549415
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.03.042
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