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Early activation of mTORC1 signalling in response to mechanical overload is independent of phosphoinositide 3-kinase/Akt signalling

ABSTRACT: The mammalian target of rapamycin complex 1 (mTORC1) functions as a central integrator of a wide range of signals that modulate protein metabolism and cell growth. However, the contributions of individual pathways regulating mTORC1 activity in skeletal muscle are poorly defined. The purpos...

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Detalhes bibliográficos
Main Authors: Miyazaki, Mitsunori, McCarthy, John J, Fedele, Mark J, Esser, Karyn A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099033/
https://ncbi.nlm.nih.gov/pubmed/21300751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2011.205658
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