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REDD2 is enriched in skeletal muscle and inhibits mTOR signaling in response to leucine and stretch
The protein kinase mammalian target of rapamycin (mTOR) is well established as a key regulator of skeletal muscle size. In this study, we determined that the stress responsive gene REDD2 (regulated in development and DNA damage responses 2) is a negative regulator of mTOR signaling and is expressed...
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| Hlavní autoři: | , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Physiological Society
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2660267/ https://ncbi.nlm.nih.gov/pubmed/19129461 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00464.2008 |
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