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Regulation of mTORC1 Signaling by Src Kinase Activity Is Akt1-Independent in RSV-Transformed Cells

Increased activity of the Src tyrosine protein kinase that has been observed in a large number of human malignancies appears to be a promising target for drug therapy. In the present study, a critical role of the Src activity in the deregulation of mTOR signaling pathway in Rous sarcoma virus (RSV)-...

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Detalhes bibliográficos
Main Authors: Vojtěchová, Martina, Turečková, Jolana, Kučerová, Dana, Šloncová, Eva, Vachtenheim, Jiří, Tuháčková, Zdena
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2244684/
https://ncbi.nlm.nih.gov/pubmed/18283331
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