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The Development and Use of Clickable Activity Based Protein Profiling Agents for Protein Arginine Deiminase 4
The Protein Arginine Deiminases (PAD), which catalyze the hydrolysis of peptidyl-arginine to form peptidyl-citrulline, are potential targets for the development of a Rheumatoid Arthritis (RA) therapeutic, as well as other human diseases including colitis and cancer. Additionally, these enzymes, and...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098906/ https://ncbi.nlm.nih.gov/pubmed/21265574 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb1003515 |
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