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Lsm1 promotes genomic stability by controlling histone mRNA decay

Lsm1 forms part of a cytoplasmic protein complex, Lsm1-7-Pat1, involved in the degradation of mRNAs. Here, we show that Lsm1 has an important role in promoting genomic stability in Saccharomyces cerevisiae. Budding yeast cells lacking Lsm1 are defective in recovery from replication-fork stalling and...

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Autori principali: Herrero, Ana B, Moreno, Sergio
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2011
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098488/
https://ncbi.nlm.nih.gov/pubmed/21487390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.117
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