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Lsm1 promotes genomic stability by controlling histone mRNA decay
Lsm1 forms part of a cytoplasmic protein complex, Lsm1-7-Pat1, involved in the degradation of mRNAs. Here, we show that Lsm1 has an important role in promoting genomic stability in Saccharomyces cerevisiae. Budding yeast cells lacking Lsm1 are defective in recovery from replication-fork stalling and...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3098488/ https://ncbi.nlm.nih.gov/pubmed/21487390 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.117 |
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