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The decapping activator Edc3 and the Q/N-rich domain of Lsm4 function together to enhance mRNA stability and alter mRNA decay pathway dependence in Saccharomyces cerevisiae

The rate and regulation of mRNA decay are major elements in the proper control of gene expression. Edc3 and Lsm4 are two decapping activator proteins that have previously been shown to function in the assembly of RNA granules termed P bodies. Here, we show that deletion of edc3, when combined with a...

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Bibliografski detalji
Izdano u:Biol Open
Glavni autori: Huch, Susanne, Müller, Maren, Muppavarapu, Mridula, Gommlich, Jessie, Balagopal, Vidya, Nissan, Tracy
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists Ltd 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5087693/
https://ncbi.nlm.nih.gov/pubmed/27543059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.020487
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