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A non-canonical role for the EDC4 decapping factor in regulating MARF1-mediated mRNA decay
EDC4 is a core component of processing (P)-bodies that binds the DCP2 decapping enzyme and stimulates mRNA decay. EDC4 also interacts with mammalian MARF1, a recently identified endoribonuclease that promotes oogenesis and contains a number of RNA binding domains, including two RRMs and multiple LOT...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7279887/ https://ncbi.nlm.nih.gov/pubmed/32510323 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.54995 |
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