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Scavenger Decapping Activity Facilitates 5′ to 3′ mRNA Decay

mRNA degradation occurs through distinct pathways, one primarily from the 5′ end of the mRNA and the second from the 3′ end. Decay from the 3′ end generates the m(7)GpppN cap dinucleotide, which is subsequently hydrolyzed to m(7)Gp and ppN in Saccharomyces cerevisiae by a scavenger decapping activit...

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Detalhes bibliográficos
Main Authors: Liu, Hudan, Kiledjian, Megerditch
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280280/
https://ncbi.nlm.nih.gov/pubmed/16260594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.9764-9772.2005
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