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Scavenger Decapping Activity Facilitates 5′ to 3′ mRNA Decay

mRNA degradation occurs through distinct pathways, one primarily from the 5′ end of the mRNA and the second from the 3′ end. Decay from the 3′ end generates the m(7)GpppN cap dinucleotide, which is subsequently hydrolyzed to m(7)Gp and ppN in Saccharomyces cerevisiae by a scavenger decapping activit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Hudan, Kiledjian, Megerditch
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280280/
https://ncbi.nlm.nih.gov/pubmed/16260594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.9764-9772.2005
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