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Scavenger Decapping Activity Facilitates 5′ to 3′ mRNA Decay

mRNA degradation occurs through distinct pathways, one primarily from the 5′ end of the mRNA and the second from the 3′ end. Decay from the 3′ end generates the m(7)GpppN cap dinucleotide, which is subsequently hydrolyzed to m(7)Gp and ppN in Saccharomyces cerevisiae by a scavenger decapping activit...

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Bibliografische gegevens
Hoofdauteurs: Liu, Hudan, Kiledjian, Megerditch
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1280280/
https://ncbi.nlm.nih.gov/pubmed/16260594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.22.9764-9772.2005
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