Viral CTL Escape Mutants Are Generated in Lymph Nodes and Subsequently Become Fixed in Plasma and Rectal Mucosa during Acute SIV Infection of Macaques

SIV(mac239) infection of rhesus macaques (RMs) results in AIDS despite the generation of a strong antiviral cytotoxic T lymphocyte (CTL) response, possibly due to the emergence of viral escape mutants that prevent recognition of infected cells by CTLs. To determine the anatomic origin of these SIV m...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Vanderford, Thomas H., Bleckwehl, Chelsea, Engram, Jessica C., Dunham, Richard M., Klatt, Nichole R., Feinberg, Mark B., Garber, David A., Betts, Michael R., Silvestri, Guido
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Public Library of Science 2011
विषय:
Research Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098234/
https://ncbi.nlm.nih.gov/pubmed/21625590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002048
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