Calpain-Catalyzed Proteolysis of Human dUTPase Specifically Removes the Nuclear Localization Signal Peptide

BACKGROUND: Calpain proteases drive intracellular signal transduction via specific proteolysis of multiple substrates upon Ca(2+)-induced activation. Recently, dUTPase, an enzyme essential to maintain genomic integrity, was identified as a physiological calpain substrate in Drosophila cells. Here we...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
Main Authors: Bozóky, Zoltán, Róna, Gergely, Klement, Éva, Medzihradszky, Katalin F., Merényi, Gábor, Vértessy, Beáta G., Friedrich, Peter
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2011
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3098232/
https://ncbi.nlm.nih.gov/pubmed/21625588
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0019546
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki