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Activation of the cryptic DNA binding function of mutant forms of p53.

Wild type p53 assembles into a latent multiprotein complex which can be activated for sequence-specific DNA binding in vitro by proteins targeting the carboxy-terminal domain. Using an optimized system coupling the post-translational modification of wild type p53 to activation of sequence specific D...

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Bibliografski detalji
Glavni autori: Hupp, T R, Meek, D W, Midgley, C A, Lane, D P
Format: Artigo
Jezik:Inglês
Izdano: 1993
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC309751/
https://ncbi.nlm.nih.gov/pubmed/8341590
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