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Activation of the cryptic DNA binding function of mutant forms of p53.
Wild type p53 assembles into a latent multiprotein complex which can be activated for sequence-specific DNA binding in vitro by proteins targeting the carboxy-terminal domain. Using an optimized system coupling the post-translational modification of wild type p53 to activation of sequence specific D...
Tallennettuna:
| Päätekijät: | , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
1993
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| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC309751/ https://ncbi.nlm.nih.gov/pubmed/8341590 |
| Tagit: |
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