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Single molecule analysis reveals three phases of DNA degradation by an exonuclease

λ exonuclease degrades one strand of duplex DNA in the 5’-3’ direction to generate a 3’ overhang required for recombination. Its ability to hydrolyze thousands of nucleotides processively is attributed to its ring structure and most studies have focused on the processive phase. Here, we use single m...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Lee, Gwangrog, Yoo, Jungmin, Leslie, Benjamin J., Ha, Taekjip
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3097319/
https://ncbi.nlm.nih.gov/pubmed/21552271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.561
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