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Extreme bendability of sub-100 bp long DNA revealed by single molecule cyclization
The classical view of DNA posits that DNA must be stiff below the persistence length (<150 bp) but recent studies addressing this have yielded contradictory results. We developed a fluorescence-based, protein-free assay for studying the cyclization of single DNA molecules in real time. The assay...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3565842/ https://ncbi.nlm.nih.gov/pubmed/22936778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1224139 |
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