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Single molecule analysis reveals three phases of DNA degradation by an exonuclease
λ exonuclease degrades one strand of duplex DNA in the 5’-3’ direction to generate a 3’ overhang required for recombination. Its ability to hydrolyze thousands of nucleotides processively is attributed to its ring structure and most studies have focused on the processive phase. Here, we use single m...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3097319/ https://ncbi.nlm.nih.gov/pubmed/21552271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.561 |
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