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Metformin Induces Both Caspase-Dependent and Poly(ADP-ribose) Polymerase-Dependent Cell Death in Breast Cancer Cells
There is substantial evidence that metformin, a drug used to treat type 2 diabetics, is potentially useful as a therapeutic agent for cancer. However, a better understanding of the molecular mechanisms through which metformin promotes cell cycle arrest and cell death of cancer cells is necessary. It...
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| Formato: | Artigo |
| Idioma: | Inglês |
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2011
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3096726/ https://ncbi.nlm.nih.gov/pubmed/21422199 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-10-0343 |
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