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Multiple Promoters in the WNK1 Gene: One Controls Expression of a Kidney-Specific Kinase-Defective Isoform

WNK1 is a serine-threonine kinase, the expression of which is affected in pseudohypoaldosteronism type II, a Mendelian form of arterial hypertension. We characterized human WNK1 transcripts to determine the molecular mechanisms governing WNK1 expression. We report the presence of two promoters gener...

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Detalhes bibliográficos
Main Authors: Delaloy, Celine, Lu, Jingyu, Houot, Anne-Marie, Disse-Nicodeme, Sandra, Gasc, Jean-Marie, Corvol, Pierre, Jeunemaitre, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC309643/
https://ncbi.nlm.nih.gov/pubmed/14645531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.24.9208-9221.2003
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