Cardiovascular Expression of the Mouse WNK1 Gene during Development and Adulthood Revealed by a BAC Reporter Assay

Large deletions in WNK1 are associated with inherited arterial hypertension. WNK1 encodes two types of protein: a kidney-specific isoform (KS-WNK1) lacking kinase activity and a ubiquitously expressed full-length isoform (L-WNK1) with serine threonine kinase activity. Disease is thought to result fr...

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Detalhes bibliográficos
Main Authors: Delaloy, Céline, Hadchouel, Juliette, Imbert-Teboul, Martine, Clemessy, Maud, Houot, Anne-Marie, Jeunemaitre, Xavier
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2006
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1698764/
https://ncbi.nlm.nih.gov/pubmed/16816365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2006.051290
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