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Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?

A great deal of evidence supports a role for mitochondrial dysfunction in the pathogenesis of Parkinson's disease (PD), although the origin of the mitochondrial dysfunction in PD remains unclear. Expression of mitochondrial DNA (mtDNA) from PD patients in “cybrid” cell lines recapitulates the m...

詳細記述

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書誌詳細
主要な著者: Clark, Joanne, Dai, Ying, Simon, David K.
フォーマット: Artigo
言語:Inglês
出版事項: SAGE-Hindawi Access to Research 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096076/
https://ncbi.nlm.nih.gov/pubmed/21603185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/659694
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