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Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?

A great deal of evidence supports a role for mitochondrial dysfunction in the pathogenesis of Parkinson's disease (PD), although the origin of the mitochondrial dysfunction in PD remains unclear. Expression of mitochondrial DNA (mtDNA) from PD patients in “cybrid” cell lines recapitulates the m...

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Sonraí Bibleagrafaíochta
Main Authors: Clark, Joanne, Dai, Ying, Simon, David K.
Formáid: Artigo
Teanga:Inglês
Foilsithe: SAGE-Hindawi Access to Research 2011
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096076/
https://ncbi.nlm.nih.gov/pubmed/21603185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/659694
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