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Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?

A great deal of evidence supports a role for mitochondrial dysfunction in the pathogenesis of Parkinson's disease (PD), although the origin of the mitochondrial dysfunction in PD remains unclear. Expression of mitochondrial DNA (mtDNA) from PD patients in “cybrid” cell lines recapitulates the m...

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Bibliografske podrobnosti
Main Authors: Clark, Joanne, Dai, Ying, Simon, David K.
Format: Artigo
Jezik:Inglês
Izdano: SAGE-Hindawi Access to Research 2011
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096076/
https://ncbi.nlm.nih.gov/pubmed/21603185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/659694
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