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Do Somatic Mitochondrial DNA Mutations Contribute to Parkinson's Disease?

A great deal of evidence supports a role for mitochondrial dysfunction in the pathogenesis of Parkinson's disease (PD), although the origin of the mitochondrial dysfunction in PD remains unclear. Expression of mitochondrial DNA (mtDNA) from PD patients in “cybrid” cell lines recapitulates the m...

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Detalhes bibliográficos
Main Authors: Clark, Joanne, Dai, Ying, Simon, David K.
Formato: Artigo
Idioma:Inglês
Publicado em: SAGE-Hindawi Access to Research 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096076/
https://ncbi.nlm.nih.gov/pubmed/21603185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2011/659694
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