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Intersection of the unfolded protein response and hepatic lipid metabolism

The liver plays a central role in whole-body lipid metabolism by governing the synthesis, oxidization, transport and excretion of lipids. The unfolded protein response (UPR) was identified as a signal transduction system that is activated by ER stress. Recent studies revealed a critical role of the...

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Bibliographic Details
Main Authors: Lee, Ann-Hwee, Glimcher, Laurie H.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3096022/
https://ncbi.nlm.nih.gov/pubmed/19468685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00018-009-0049-8
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