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In vivo positron emission tomography imaging with [(11)C]ABP688: Binding variability and specificity for the metabotropic glutamate receptor subtype 5 in baboons
PURPOSE: Metabotropic glutamate receptor subtype 5 (mGluR5) dysfunction has been implicated in several disorders. [(11)C]ABP688, a Positron Emission Tomography (PET) ligand targeting mGluR5, could be a valuable tool in the development of novel therapeutics for these disorders by establishing in vivo...
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| Główni autorzy: | , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2011
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095762/ https://ncbi.nlm.nih.gov/pubmed/21279350 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-010-1723-7 |
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