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Secondary mutations of BRCA1/2 and drug resistance
Inherited mutations in the tumor suppressor genes BRCA1 and BRCA2 cause increased risk of developing various cancers, especially breast and ovarian cancers. Tumors that develop in patients with inherited BRCA1/2 mutations are generally believed to be BRCA1/2 deficient. Cancer cells with BRCA1/2 defi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3095365/ https://ncbi.nlm.nih.gov/pubmed/21205087 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1349-7006.2010.01840.x |
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