Inhibition of 2′,5′-Oligoadenylate Synthetase Expression and Function by the Human Cytomegalovirus ORF94 Gene Product

The human cytomegalovirus (HCMV) ORF94 gene product has been reported to be expressed during both productive and latent phases of infection, although its function is unknown. We report that expression of pORF94 leads to decreased 2′,5′-oligoadenylate synthetase (OAS) expression in transfected cells...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Tan, Joanne C. G., Avdic, Selmir, Cao, John Z., Mocarski, Edward S., White, Kirsten L., Abendroth, Allison, Slobedman, Barry
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society for Microbiology 2011
Θέματα:
Pathogenesis and Immunity
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094971/
https://ncbi.nlm.nih.gov/pubmed/21450824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02463-10
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