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Inhibition of 2′,5′-Oligoadenylate Synthetase Expression and Function by the Human Cytomegalovirus ORF94 Gene Product

The human cytomegalovirus (HCMV) ORF94 gene product has been reported to be expressed during both productive and latent phases of infection, although its function is unknown. We report that expression of pORF94 leads to decreased 2′,5′-oligoadenylate synthetase (OAS) expression in transfected cells...

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Detalhes bibliográficos
Main Authors: Tan, Joanne C. G., Avdic, Selmir, Cao, John Z., Mocarski, Edward S., White, Kirsten L., Abendroth, Allison, Slobedman, Barry
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094971/
https://ncbi.nlm.nih.gov/pubmed/21450824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02463-10
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