Inhibition of 2′,5′-Oligoadenylate Synthetase Expression and Function by the Human Cytomegalovirus ORF94 Gene Product

The human cytomegalovirus (HCMV) ORF94 gene product has been reported to be expressed during both productive and latent phases of infection, although its function is unknown. We report that expression of pORF94 leads to decreased 2′,5′-oligoadenylate synthetase (OAS) expression in transfected cells...

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Bibliografiske detaljer
Main Authors: Tan, Joanne C. G., Avdic, Selmir, Cao, John Z., Mocarski, Edward S., White, Kirsten L., Abendroth, Allison, Slobedman, Barry
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2011
Fag:
Pathogenesis and Immunity
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094971/
https://ncbi.nlm.nih.gov/pubmed/21450824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02463-10
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