Inhibition of 2′,5′-Oligoadenylate Synthetase Expression and Function by the Human Cytomegalovirus ORF94 Gene Product

The human cytomegalovirus (HCMV) ORF94 gene product has been reported to be expressed during both productive and latent phases of infection, although its function is unknown. We report that expression of pORF94 leads to decreased 2′,5′-oligoadenylate synthetase (OAS) expression in transfected cells...

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Bibliografski detalji
Glavni autori: Tan, Joanne C. G., Avdic, Selmir, Cao, John Z., Mocarski, Edward S., White, Kirsten L., Abendroth, Allison, Slobedman, Barry
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2011
Teme:
Pathogenesis and Immunity
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094971/
https://ncbi.nlm.nih.gov/pubmed/21450824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02463-10
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