Degringolade, a SUMO-targeted ubiquitin ligase, inhibits Hairy/Groucho-mediated repression

Transcriptional cofactors are essential for proper embryonic development. One such cofactor in Drosophila, Degringolade (Dgrn), encodes a RING finger/E3 ubiquitin ligase. Dgrn and its mammalian ortholog RNF4 are SUMO-targeted ubiquitin ligases (STUbLs). STUbLs bind to SUMOylated proteins via their S...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Abed, Mona, Barry, Kevin C, Kenyagin, Dorit, Koltun, Bella, Phippen, Taryn M, Delrow, Jeffrey J, Parkhurst, Susan M, Orian, Amir
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094120/
https://ncbi.nlm.nih.gov/pubmed/21343912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2011.42
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker