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SUMO-targeted ubiquitin ligases in genome stability

We identify the SUMO-Targeted Ubiquitin Ligase (STUbL) family of proteins and propose that STUbLs selectively ubiquitinate sumoylated proteins and proteins that contain SUMO-like domains (SLDs). STUbL recruitment to sumoylated/SLD proteins is mediated by tandem SUMO interaction motifs (SIMs) within...

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Detalhes bibliográficos
Main Authors: Prudden, John, Pebernard, Stephanie, Raffa, Grazia, Slavin, Daniela A, Perry, J Jefferson P, Tainer, John A, McGowan, Clare H, Boddy, Michael N
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2230673/
https://ncbi.nlm.nih.gov/pubmed/17762865
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601838
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