Nse1 RING-like Domain Supports Functions of the Smc5-Smc6 Holocomplex in Genome Stability

The Smc5-Smc6 holocomplex plays essential but largely enigmatic roles in chromosome segregation, and facilitates DNA repair. The Smc5-Smc6 complex contains six conserved non-SMC subunits. One of these, Nse1, contains a RING-like motif that often confers ubiquitin E3 ligase activity. We have function...

Full description

Saved in:
Bibliographic Details
Main Authors: Pebernard, Stephanie, Perry, J. Jefferson P., Tainer, John A., Boddy, Michael N.
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 2008
Subjects:
Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555936/
https://ncbi.nlm.nih.gov/pubmed/18667531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0226
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items