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Nse1 RING-like Domain Supports Functions of the Smc5-Smc6 Holocomplex in Genome Stability
The Smc5-Smc6 holocomplex plays essential but largely enigmatic roles in chromosome segregation, and facilitates DNA repair. The Smc5-Smc6 complex contains six conserved non-SMC subunits. One of these, Nse1, contains a RING-like motif that often confers ubiquitin E3 ligase activity. We have function...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Cell Biology
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2555936/ https://ncbi.nlm.nih.gov/pubmed/18667531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-02-0226 |
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