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Localization of Smc5/6 to centromeres and telomeres requires heterochromatin and SUMO, respectively
The Smc5/6 holocomplex executes key functions in genome maintenance that include ensuring the faithful segregation of chromosomes at mitosis and facilitating critical DNA repair pathways. Smc5/6 is essential for viability and therefore, dissecting its chromosome segregation and DNA repair roles has...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2585169/ https://ncbi.nlm.nih.gov/pubmed/18923417 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.220 |
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