ERBB Receptor Activation Is Required for Profibrotic Responses to Transforming Growth Factor β

Engagement of the transforming growth factor-β (TGF-β) receptor complex activates multiple signaling pathways that play crucial roles in both health and disease. TGF-β is a key regulator of fibrogenesis and cancer-associated desmoplasia; however, its exact mode of action in these pathologic processe...

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Bibliografiske detaljer
Main Authors: Andrianifahanana, Mahefatiana, Wilkes, Mark C., Repellin, Claire E., Edens, Maryanne, Kottom, Theodore J., Rahimi, Rod A., Leof, Edward B.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093933/
https://ncbi.nlm.nih.gov/pubmed/20841477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0232
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