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Collagen Fragments Inhibit Hyaluronan Synthesis in Skin Fibroblasts in Response to Ultraviolet B (UVB): NEW INSIGHTS INTO MECHANISMS OF MATRIX REMODELING

UVB irradiation causes characteristic features of skin aging including remodeling of the dermal extracellular matrix. A key feature during this process is the up-regulation of matrix metalloproteinases and cleavage of collagen. Hyaluronic acid (HA), a major component of the dermal matrix, decreases...

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Autors principals: Röck, Katharina, Grandoch, Maria, Majora, Marc, Krutmann, Jean, Fischer, Jens W.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3093899/
https://ncbi.nlm.nih.gov/pubmed/21454612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.201665
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